Abstract
Metal complexes with quinoxaline derivatives were synthesized by the condensation of quinoxaline-2-carboxaldehyde with substituted 5- aminoflavones. The synthesized metal complexes were characterized by elemental analysis, IR, 1H-NMR, UV-Vis., molar conductance, magnetic moment and electrochemical studies. Based on the magnetic moment and electronic spectral data, square planar geometry has been proposed for all the complexes. The antimicrobial screening of the ligands and their metal complexes suggested that for the complexes showed higher activities than the free ligands. The DNA binding behavior of complexes with CT DNA has been studied using electronic absorption spectra and cyclic voltammetry techniques. The DNA binding constants indicated that all metal complexes interacted with DNA through intercalation binding mode. Superoxide dismutase activity of the metal complexes were performed and discussed in detail